Oligonucleotide CRO&CDMO
Shanghai Aurisco Biotech Co., Ltd is focus on providing CRO/CDMO services. We provide APIs service from discovery, clinical trials to commercial stage.
With 20+ years’ experience of API manufacturing, our oligo platform has a dedicated team of 30+ scientists in oligonucleotide field,and equips with advanced and equipment,accelerating clients’ drugs to the global market.
The process chemistry, analytical, and regulations teams collaborate to provide clients with a fast, efficient, and flexible integrated solution for oligonucleotide development.
Advanced equipments
Aurisco oligonucleotide platform is equipped with Cytiva ÄKTA oligonucleotide solid-phase synthesizer and purification equipment,with capacity from gram to KG scale.
In addition, analytical equipments including UPLC-QTof, UPLC-MS, UPLC provide support for oligonucleotide structure characterization, analytical method development and validation,GMP manufacturing and stability study.
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Lab scale(grams)
ÄKTA OligoPilot 10, 100ÄKTA flow 6 -
Pilot scale (hundreds grams)
OligoPilot™ 2000Novasep Hipersep™Sartoflow advancedGenesis 35L -
Key analytical equipment
Headspace GCUHPLC, UPLCUPLC-UV-MS, UHPLC-TOF-MS
Manufacturing capbility
Custom DNA/RNA - API Manufacturing Services
Aurisco provides oligonucleotide synthesis services as follow
- 01ASO
- 02PMO
- 03siRNA
- 04miRNA
- 05Other modified oligonucleotides
- 06Decoy ODNs
- 07Aptamer
- 08Locked nucleic acid (LNA)
- 09DNA Probe, RNA Probe
- 10Others：modified nucleosides, nucleotides; Delivery System chemicals
Oligonucleotide Service includes
- Process Developing and Optimization
- mg to KG scale
- Analytical characterization, test method development and validation, IPC & release testing
- Stability studies compliant to ICH
- RA support for worldwide
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