Shanghai Aurisco Biotech Co., Ltd is focus on providing CRO/CDMO services. We provide APIs service from discovery, clinical trialsto commercial stage.
With 20+ years’ experience of API manufacturing, our oligo platform has a dedicated team of 30+ scientists in oligonucleotide field, accelerating clients’ drugs to the global market.
The process chemistry, analytical, and regulations teams collaborate to provide clients with a fast, efficient, and flexible integrated solution for oligonucleotide development.
Aurisco oligonucleotide platform is equipped with Cytiva ÄKTA oligonucleotide solid-phase synthesizer and purification equipments,with capacity from gram to KG scale.
In addition, analytical equipments including UPLC-QTof, UPLC-MS, UPLC provide support for oligonucleotide structure characterization, analytical method development and validation,GMP manufacturing and stability study.
Lab scale(grams)ÄKTA OligoPilot 10, 100ÄKTA flow 6
Pilot scale (hundreds grams)OligoPilot™ 2000Novasep Hipersep™Sartoflow advancedGenesis 35L
Key analytical equipmentHeadspace GCUHPLC, UPLCUPLC-UV-MS, UHPLC-TOF-MS
Custom DNA/RNA - API Manufacturing Services
Aurisco provides oligonucleotide synthesis services as follow
- 05Other modified oligonucleotides
- 06Decoy ODNs
- 08Locked nucleic acid (LNA)
- 09DNA Probe, RNA Probe
- 10Others：modified nucleosides, nucleotides; Delivery System chemicals
Oligonucleotide Service includes
- Process Developing and Optimization
- mg to KG scale
- Analytical characterization, test method development and validation, IPC & release testing
- Stability studies compliant to ICH
- RA support for worldwide